BENITIONSClinical Trial Intelligence

A Study of Dengue Vaccine in Healthy Children, Teenagers and Adults in India

3상 완료 NCT06060067

대상 질환Healthy Volunteers
임상 단계3상
스폰서Takeda
상태완료
참여자 수480 명
중재(약물)TDV
시작일2024년 3월 29일
완료일2025년 5월 5일
결과 공개일2026년 5월 29일

요약

The main aims of the study are to learn about side effects and a participant's immune response to Takeda's Dengue Vaccine when given twice within 3 months. Participants will receive 2 doses of their randomized treatment (vaccine or placebo). Children, teenagers and adults will receive one dose of either the vaccine or placebo on Day 1 and the second dose of either the vaccine or placebo 3 months later. Up to 4 blood samples will be taken throughout the study. During the study, participants will visit their study clinic 6 times.

Number of Participants With Solicited Local (Injection Site) Adverse Events (AEs) by Severity Within 7 Days Post-vaccination at Day 1 for Age Group Less Than 6 Years

Within 7 days post-vaccination at Day 1 · Participants

Cohort 2: ≥4 to <6 Years Age Group: TDV42 Participants
Cohort 2: ≥4 to <6 Years Age Group: Placebo10 Participants
Cohort 2: ≥4 to <6 Years Age Group: TDV4 Participants
Cohort 2: ≥4 to <6 Years Age Group: Placebo4 Participants
Cohort 2: ≥4 to <6 Years Age Group: TDV0 Participants
Cohort 2: ≥4 to <6 Years Age Group: Placebo0 Participants

Number of Participants With Solicited Local (Injection Site) AEs by Severity Within 7 Days Post-vaccination at Day 1 for Age Group 6 Years and Over

Within 7 days post-vaccination at Day 1 · Participants

Cohort 1: ≥18 to ≤60 Years Age Group: TDV152 Participants
Cohort 1: ≥18 to ≤60 Years Age Group: Placebo53 Participants
Cohort 2: ≥6 to <18 Years Age Group: TDV119 Participants
Cohort 2: ≥6 to <18 Years Age Group: Placebo42 Participants
Cohort 1: ≥18 to ≤60 Years Age Group: TDV25 Participants
Cohort 1: ≥18 to ≤60 Years Age Group: Placebo7 Participants

Number of Participants With Solicited Local (Injection Site) AEs by Severity Within 7 Days Post-vaccination at Day 90 for Age Group Less Than 6 Years

Within 7 days post-vaccination at Day 90 · Participants

Cohort 2: ≥4 to <6 Years Age Group: TDV44 Participants
Cohort 2: ≥4 to <6 Years Age Group: Placebo14 Participants
Cohort 2: ≥4 to <6 Years Age Group: TDV2 Participants
Cohort 2: ≥4 to <6 Years Age Group: Placebo0 Participants
Cohort 2: ≥4 to <6 Years Age Group: TDV0 Participants
Cohort 2: ≥4 to <6 Years Age Group: Placebo0 Participants

BENITIONS에서 보기 ClinicalTrials.gov 원문 보기

전체 임상

이 페이지는 ClinicalTrials.gov의 공개 데이터를 정리한 것입니다. 의학적 조언이 아니며 투자 권유나 자문도 아닙니다. 반드시 전문의와 상담하세요.