BENITIONSClinical Trial Intelligence

Vitamin D and Physical Activity on Bone Health

2상 진행 중(모집 완료) NCT01419730

대상 질환Bone Metabolism Biomarkers, Bone Mineral Density, Physical Fitness
임상 단계2상
스폰서University of Rochester
상태진행 중(모집 완료)
참여자 수191 명
중재(약물)Vitamin D3, Physical Activity
시작일2011년 8월
완료일2024년 12월 30일
결과 공개일2026년 8월 5일

요약

This research will examine the effectiveness of vitamin D or placebo (the placebo is a tablet that looks like Vitamin D study drug, but has no Vitamin D study drug in it), with and without physical activity (walking and progressive resistance exercise), in treating bone loss in women who have undergone treatment for breast cancer. The investigators would also like to find out if the physical activity program improves cardiovascular fitness, energy expenditure, muscular strength, muscle mass, and balance. One hundred five (105) subjects are expected to take part in this study. The investigators don't know if bone loss in breast cancer survivors should be treated differently than bone loss in other women.

Measure the Amount of Bone Mineral Density Loss in Non-metastatic Breast Cancer Patients Receiving a High Dose Vitamin D Therapy Along With a Structured Home-based Walking and Progressive Resistance Exercise Program.

24 weeks · Change in Hip BMD g/cm^2

High Dose Vitamin D-0.0015 ± 0.0045 Change in Hip BMD g/cm^2
High Dose Vitamin D + Exercise-0.0013 ± 0.0044 Change in Hip BMD g/cm^2
Control-0.0163 ± 0.0058 Change in Hip BMD g/cm^2
p-value0.064
F Statistic2.838

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