ALS Clinical Trial Results

Browse clinical trials for ALS by phase, sponsor and reported results. Data from ClinicalTrials.gov.

• Extension Study Following the Studies MT-1186-A03 or A04 to Evaluate the Safety of Oral Edaravone in Subjects
  Phase 3 · Shionogi · Completed · Feb 3, 2025
• Expanded Controlled Study of Safety and Efficacy of MCI-186 in Patients With Amyotrophic Lateral Sclerosis (AL
  Phase 3 · Shionogi · Completed · Jun 4, 2018
• Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS)
  Phase 3 · Shionogi · Completed · May 17, 2017
• Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS) Who Met Severity Cla
  Phase 3 · Shionogi · Completed · Dec 20, 2017
• Phase 3 Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis
  Phase 3 · Shionogi · Completed · Dec 31, 2018
• Efficacy and Safety Study of Oral Edaravone Administered in Subjects With ALS
  Phase 3 · Shionogi · Terminated · Mar 27, 2025
• Safety Extension Study of Oral Edaravone Administered in Subjects With Amyotrophic Lateral Sclerosis (ALS)
  Phase 3 · Shionogi · Completed · Aug 28, 2024
• Clinical Pharmacology Study of Oral Edaravone in Amyotrophic Lateral Sclerosis Patients With Gastrostomy
  Phase 1 · Shionogi · Completed · Jan 24, 2024
• Clinical Pharmacology Study of Oral Edaravone in Patients With Amyotrophic Lateral Sclerosis
  Phase 1 · Shionogi · Completed · Jan 24, 2024
• Neurodegenerative Alzheimer's Disease and Amyotrophic Lateral Sclerosis (NADALS) Basket Trial
  Phase 1/2 · Massachusetts General Hospital · Completed · Jun 30, 2026
• Ph1 T-Regulatory Cells in Amyotrophic Lateral Sclerosis
  Phase 1 · The Methodist Hospital Research Institute · Completed · Jun 17, 2026
• Efficacy and Safety Extension Study of Oral Edaravone Administered in Subjects With ALS
  Phase 3 · Tanabe Pharma America, Inc. · Terminated · Mar 27, 2025
• Efficacy and Safety Study of MYOBLOC® in the Treatment of Sialorrhea in Adult Subjects
  Phase 3 · Solstice Neurosciences, LLC, a subsidiary of US WorldMeds, LLC · Completed · Aug 15, 2019
• Intrathecal Autologous Adipose-derived Mesenchymal Stromal Cells for Amyotrophic Lateral Sclerosis (ALS)
  Phase 2 · Mayo Clinic · Active, not recruiting · Apr 2, 2025
• HEALEY ALS Platform Trial - Regimen G DNL343
  Phase 2/3 · Merit E. Cudkowicz, MD · Completed · Jan 28, 2026

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